Ohio-born jam band, The Werks just officially dropped their newest release, Live From The Werk Out 2016. The live album constitutes some of their best performances from their annual festival, The Werk Out, last year in Thornville, OH.After not dropping any official releases in over a year, Live From The Werk Out 2016 is an eight-track, two-hour sonic oasis for thirsty fans. The full album is available for download via the band’s Bandcamp using a “name your price” rate . A preview of the album is available via SoundCloud, which you can hear for yourself below!
For the enduring fans of the Wisconsin football team – and the team itself – nobody phrased the feeling any better than J.J. Watt did following the Badgers’ 70-23 exercise of supremacy over Northwestern Saturday.“When you have a chance to win a Big Ten championship, that doesn’t come every year, that doesn’t necessarily come every decade,” he said.It certainly doesn’t.Not but 9 years old, I can just barely remember the images and sounds from the last time Wisconsin triumphed in the Rose Bowl after taking the conference title. In fact, as I’m looking back at this old memory, I can’t even say with confidence whether I’m actually thinking of the 1999 or 2000 edition of the Ron Dayne train and the powerhouse team that ran with him all the way to Granddaddy Glory.After the glory days of the ’90s though, the Badgers were mostly out of the spotlight. As a lifelong Wisconsinite and Badger fan, over those years it generally felt like another Big Ten title and Rose Bowl bid could be had in the future but not necessarily during any given season. It was all about just waiting for the pendulum to eventually swing back.Then Hall of Fame coach Barry Alvarez left. And as the years passed by, sour sentiments brewed under newbie Bret Bielema’s head coaching seat. But that was before this year.So an accomplishment like this means a lot to Badger Nation. This program is not like one of Ohio State’s, where this sort of thing has become the status quo.Over the last seven games, the Badgers have been as unstoppable as a rhinoceros running downhill. They truly deserve to call themselves Big Ten champions and join the chatter concerning who’s the best in the country. And I will be there to talk them up whenever that conversation starts.But, as a fan, there’s still one thing that’s kind of bothering me, and it’s that all three teams invited to the Big Ten podium are standing at the top, No. 1 spot.I imagine many Badger fans feel similarly. Wisconsin is probably the hottest team in the country right now, it’s made fools out of other teams and the general consensus (even outside Wisconsin) is that the Cardinal & White are the Big Ten’s No. 1 team.You can’t tell me that if a Big Ten trophy was presented to Bucky, Sparty and Brutus, that they wouldn’t all give each other a slight look of resentment (or perhaps a shoulder-nudge) before holding it up confidently.For some reason, this reminds me of the 2007-08 NFL season. The Packers took the NFC North and seemed poised for a Super Bowl championship that year. But there would have been one indelible stain even if they had won it all – they got swept by the Bears earlier in the season. It’s just all about casting the rivals aside and speeding far past them.What’s happened to the Badgers though, is not quite the same, sure. True to their “hottest team in the country” tag, they should be going to Pasadena for a skirmish on New Year’s Day, deservedly so.But hey, if you’re like me and feel a wee bit of irritation about splitting the crown three ways with rivals, at least we know that this will never happen again with next year’s conference championship game. How’s that for timeliness?It’s unfortunate that the title couldn’t be decided with a championship game this year. This is without doubt the first time I’ve ever felt confident in saying the Badgers could take on anyone thrown at them – even at a neutral site.As selection Sunday nears, Michigan State head coach Mark Dantanio has made a point in reminding everyone that his group beat Wisconsin “convincingly.” He’s not wrong either, but if the Badgers and Spartans could take this little tiff to Lucas Oil Stadium and settle it this weekend, the Badgers would win that game.The trailblazing that UW has performed over the last seven games is all thanks to MSU. Without that chip on Bucky’s shoulder, who knows where this team would be now. Sparty’s gone through some close calls lately and a convincing loss of their own versus Iowa. That kind of momentum would get knocked on its tail end with Wisconsin’s offense rolling like Sonic the Hedgehog.Even though Wisconsin and Ohio State would never meet to decide a Big Ten title under the future subdivisions, it’s fun to imagine a rematch. This game would be much more interesting. OSU would be the one with a chipped shoulder and there would be no intoxicating home field advantage for UW. But the Badgers never shy away from the Buckeyes.That game could probably go either way but lest we forget, the entire scenario would never happen to begin with.But really, what I guess I’m trying to say with all of this is – and with all respect to the Spartans and the Buckeyes:The Badgers should be on that podium by themselves.Elliot is a junior with an undecided major. How happy are you that UW is the Big Ten champ? Are you bothered at all that you have to share it with MSU and OSU? Email him your cheers and grumbles at [email protected]
Ibrahimovic made a massive impact in his debut season at Old Trafford, scoring 28 goals in 46 appearances across all competitions before sustaining a knee ligament injury in April last year.However, the Swedish star made a remarkable recovery to return to action in November, only to suffer a recurrence of the problem the following month.The recent arrival of Alexis Sanchez from Arsenal is likely to limit his chances for Mourinho’s side, and the Portuguese coach will not stand in Ibrahimovic’s way if he wants to move on in the final days of the January transfer window.Commenting on the exit rumours, Mourinho said: “He told me nothing about it. The first time I read or heard something about that was from the media. He never mentioned that to me so I don’t know.“Zlatan is in the last year of his contract. If that is true and Zlatan wants a future in another club in another country, we are here to help and to create conditions for that to happen, not to make his life difficult.“The last thing that Zlatan told me was that he wants to recover totally and feel ready to help the team. He is working hard to be fit. He is not injured, he is in a moment of trying to feel really ready for the demands of Premier League football.”0Shares0000(Visited 1 times, 1 visits today) 0Shares0000Ibrahimovic made a massive impact in his debut season at Old Trafford, scoring 28 goals in 46 appearances across all competitions before sustaining a knee ligament injury in April last year.MANCHESTER, United Kingdom, Jan 30 – Manchester United boss Jose Mourinho insists he will not deny Zlatan Ibrahimovic the opportunity to seek regular game time elsewhere amid reported interest from the MLS.The 36-year-old striker had been linked with a move to the United States before he joined United on a free transfer from Paris Saint-Germain in 2016.
Jul 26 2018BIOCRATES’ Technology Enables Research of Host Microbiome Interactions to Investigate Neurodegenerative DiseasesBIOCRATES Life Sciences AG, a global leader in targeted metabolomics, reported today the Alzheimer’s Disease Metabolomics Consortium’s (ADMC) new breakthrough in Alzheimer’s research, which connects the Gut-Liver-Brain axis in the development and progression of Alzheimer’s disease (AD). During the Alzheimer’s Association International Conference (AAIC), Chicago, USA, researchers reported new data on how gut bacteria and lipid metabolism may influence AD.Alzheimer’s disease is a devastating and progressive neurological disorder that affects more than 60 million people worldwide. Despite major effort by researchers, the pathophysiology of this disease is not yet fully understood. However, this week in Chicago at the AAIC, scientists showed that changes in intestinal bacterial populations or activity is associated with cognitive and brain imaging changes and atrophy in Alzheimer’s disease and that this might apply to other neuropsychiatric diseases.Utilizing technology developed by BIOCRATES, which enables readouts of the host microbiome interaction, scientists shared their breakthrough findings that liver gut metabolic defects are correlated with cognitive decline in AD. Furthermore, these findings show that liver gut metabolic defects have an influence on the pathological features of AD, including neuroinflammation and amyloid-beta deposition.The Alzheimer Disease Metabolomics Consortium (ADMC) led by Prof. Rima Kaddurah-Daouk based at Duke University Medical Center is an international consortium of renowned academic institutes that includes BIOCRATES. The ADMC was formed as part of the NIA Accelerated Medicine Partnership in Alzheimer Disease (AMP-AD) to investigate pathogenic mechanisms in AD. The consortium is mapping metabolic failures across trajectory of Alzheimer’s disease and the contribution of human metabolism and the intestinal microbiota. Research carried out by Prof. Kaddurah-Daouk of the Duke Medical Center, indicate that the microbiome in our gut seems to play a major role in AD pathogenesis.Related StoriesStudy: Surveillance for antibiotic-resistant bacteria continues to be core focus for healthcare facilitiesGetting rid of chronic infections by waking up sleeping bacteriaTAU’s new Translational Medical Research Center acquires MILabs’ VECTor PET/SPECT/CT“BIOCRATES is excited to be a part of this important study. These findings underscore the importance of metabolism in the pathogenesis of many diseases. Results like these are only possible in large-scale collaborative research approaches, which our technology is perfectly suited to support,” commented Dr. Wulf Fischer-Knuppertz, CEO of BIOCRATES. “BIOCRATES continues to develop technologies for the better and deeper understanding of the host microbiome and its implications in the pathophysiology and progression of diseases such as Alzheimer’s.”In two separate AD studies with over 1,500 individuals, Prof. Rima Kaddurah-Daouk’s team showed that Alzheimer’s patients had lower levels of liver produced primary bile acids (BA) in their blood, while secondary bile acids, which are bacterially produced and known to be cytotoxic, have been found at higher concentrations. Prof. Kaddurah-Daouk was also the first to show that serum-based primary and secondary BA metabolites correlated with amyloid, tau and neurodegeneration biomarkers for AD: Cerebrospinal fluid (CSF) biomarkers, brain atrophy (measured by MRI), and glucose metabolism providing support for a role of BA pathways in AD pathophysiology.Prof. Kaddurah-Daouk of the Duke Psychiatry and Institute for Brain Sciences added: The new data suggests that the Gut-Liver-Brain axis seems to play a major role in the development of cognitive and brain atrophy in Alzheimer’s disease. Metabolomics might contribute to an earlier diagnosis of the disease and enable effective treatments based on peripheral influences to brain pathogenesis. This might help to find out whether available drugs might work better when applied early in the disease course.” Source:https://www.biocrates.com/2-features/197-gut-liver-brain-https:/www.biocrates.com/2-features/197-gut-liver-brain-axis-alzheimers-diseaseaxis