Post-Doctoral Fellow – Myosin Phosphatase

first_imgPost-doctoral research position in Division of CardiologyUniversity of MarylandA full time Post-Doctoral fellowship position is available in thelaboratory of Dr. Steven Fisher in the Division of Cardiology atthe University of Maryland-Baltimore as of April 1, 2019. Thefederally funded project examines vascular smooth muscle geneexpression and contractility in the regulation of blood flow indevelopment and disease models. The focus is on the myosinphosphatase (MP), a critical target of signals that regulate bloodflow. Experiments will test the hypothesis that editing of MPlowers blood pressure in models of hypertension and heart failure,and will determine the mechanism(s) by which it does so. Thepost-doc will perform experiments in animal models using Cre-Loxand AAV-Crispr/Cas9 editing of MP in vivo. The AAV-Crispr/Cas9approach of editing is in pre-clinical development as a noveltherapy for humans with hypertension and heart failure. Applicantsare required to have a Ph.D. or M.D. and expertise in techniques ofcell and molecular biology. Familiarity with experimentaltechniques required for the study of small blood vessels ispreferred but not required.If interested please email a CV, a short statement of researchinterests, and the names and contact information for threereferences to:Steven Fisher, MD, Professor of Medicine and Physiology,[email protected] :Applicants are required to have a Ph.D. or M.D. and expertise intechniques of cell and molecular biology. Familiarity withexperimental techniques required for the study of small bloodvessels is preferred but not required.University of Maryland is an Equal Opportunity Employer encouragingexcellence through diversity. Qualified woman and minoritycandidates are encouraged to apply.last_img

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